| A continuous regimen of levonorgestrel/ethinyl estradiol for contraception and elimination of... |
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A continuous regimen of levonorgestrel/ethinyl estradiol for contraception and elimination of menstruation. Drugs Today (Barc). 2008 Mar;44(3):183-95 Authors: Jensen JT Clinicians and patients desiring amenorrhea for therapeutic or social reasons will find continuous-use 90 microg levonorgestrel/20 microg ethinyl estradiol to be an attractive oral contraceptive dosing option. Although other formulations of oral contraceptives can be dosed in a continuous manner off-label, the convenience of a 28-day dose pack represents a major advance that will likely increase acceptability of the strategy. The availability of FDA-approved continuous-use 90 microg levonorgestrel/20 microg ethinyl estradiol will help mainstream continuous oral contraception in the same way that Preven and Plan B helped legitimize and mainstream emergency contraception. Patients wishing to use continuous 90 microg levonorgestrel/20 microg ethinyl estradiol must recognize and accept that unscheduled breakthrough bleeding is typical during the first four to six cycles of use. Control of cycle-related symptoms may emerge as an off-label indication for use. PMID: 18536780 [PubMed - indexed for MEDLINE] Read more...             |
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