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Refusals by pharmacists to dispense emerging contraception: a critique.
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Refusals by pharmacists to dispense emerging contraception: a critique.

Obstet Gynecol. 2006 Sep;108(3):692

Authors: El-Ibiary S, Cocohoba J

PMID: 16946232 [PubMed - in process]

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MAKE LOVE, not unplanned pregnancies#that could be the slogan of our times. In 1994, half of all pregnancies were unintended, and the highest rate of such conception was among young women of color, according to the Alan Guttmacher Institute. Why#with greater birth-control options than our mothers had #are we slipping up? "It has to do with not being educated about all the contraceptive options, as well as with inconsistent use," says Valerie Montgomery Rice, M.D., director of the division of reproductive endocrinology and infertility at University of Kansas Medical Center.

But there are signs that we're taking control. Between 1982 and 1995, the proportion of Black women who were having intercourse but not using birth control fell by almost half. Furthermore, the birth rate for unmarried Black women is lower now than in any year since 1969.

New contraceptive options will continue to make it easier for us to plan parenthood. "During the next two years there will be a record launch of birth-control products in the United States," says Elof Johansson, M.D., Ph.D., vice-president and director of the Population Council's Center for Biomedical Research. Below, a look at birth-control products emerging in the new millennium. [Turn the page for a comprehensive listing of existing contraceptives.]

WHAT'S NEW FOR HER

Greater convenience and fewer side effects characterize many of the new female birth-control options.

* Lunelle You've heard of Depo Provera, a shot given every three months to prevent pregnancy. A new shot, Lunelle, is taken each month. Containing the same hormones as the Pill, it's as effective as sterilization. Unlike Depo, Lunelle impairs fertility for only a month after the last injection; Depo prevents pregnancy for three more months. Lunelle, expected to be approved by the Food and Drug Administration (FDA) soon, is not recommended for women with heart problems.

* Norplant 2 The original Norplant, the contraceptive device consisting of six thin capsules inserted just beneath the skin, prevents pregnancy for five years by releasing the hormone levonorgestrel. Norplant 2, a two-rod implant, offers protection for three years. It has been approved by the FDA but is not now marketed in the United States. Caution: Sisters using Norplant may develop keloids (thick scarring) from insertion and removal, says Yvonne S. Thornton, M.D., M.P.H., clinical professor of obstetrics and gynecology at the University of Medicine and Dentistry in Newark, New Jersey.

* Mirena Billed as a better IUD (intrauterine device), Mirena is expected to be approved for use in the United States within the next two years. The contraceptive releases levonorgestrel directly into the uterus, so less hormone is needed, reducing risk of negative side effects. It prevents pregnancy for up to five years.

* Lea's Shield Diaphragms have been around for decades, but a new version, Lea's Shield, is headed our way. The one-size-fits-all device is made of silicone rubber. The Shield is inserted like a diaphragm and covers the cervix. A one-way valve allows secretions to flow out without letting sperm in. It is expected on the market by early next year.

* Vaginal ring This flexible donut-shaped silicone-rubber device fits comfortably into the vagina, slowly releasing hormones into surrounding tissues. It can be inserted by the wearer instead of a physician and will be available in about five years,

* Gels, patches Researchers are working on gels and patches that are applied to a woman's abdomen and deliver hormones into the bloodstream through the skin. They can be used to prevent pregnancy or as hormone-replacement therapy for menopausal women. Expect a patch in about two or three years.

WHAT'S COMING FOR HIM

Partly because of physiology, men have far fewer birth-control options than women. But brothers may soon have alternatives that resemble those now available to sisters.

* No-scalpel vasectomies About 500,000 men#one out of every hundred men between ages 25 and 49#choose a vasectomy every year, and about a third are undergoing a new no-scalpel technique. How it works: A surgeon makes a tiny puncture in the scrotum to reach the sperm tubes, which are then cut and sealed. No stitches are required. The procedure, which takes about ten minutes, costs between $240 and $1,000 and may be covered by insurance.

* A male pill Researchers are developing an oral contraceptive for men that dramatically reduces sperm production. This contraceptive, which contains the hormone progestin, will be taken in combination with an injection or patch containing testosterone. It doesn't inhibit sexual desire or ability to function and will probably be on the market in five to ten years.

* Implants Like Norplant for women, a single implant is placed under the skin of the upper arm. It releases a synthetic male hormone that suppresses sperm production without impairing sex drive. These implants are being developed to prevent pregnancy for up to one, two or three years. Implants will be on the horizon in about seven to ten years.

* Immunocontraceptives This method works by stimulating antibodies that inactivate a hormone essential to sperm and testosterone production. Immunocontraception, which may be delivered by injection or in an implant, provides continuous contraception for up to one year. It may be available in ten to 15 years.

DIABETES UPDATE: If you have type-2 diabetes, talk to your physician about Avandia (rosiglitazone maleate), a new oral diabetes treatment recently approved by the Food and Drug Administration. Unlike other diabetes drugs, Avandia lowers blood-sugar levels by targeting insulin resistance, an underlying cause of type-2 diabetes. This helps the body's own insulin work more effectively. Though well tolerated in clinical trials, the most commonly reported side effects were upper-respiratory-bract infection and headache. Other side effects included weight gain, anemia and edema.

Methods Risks effectiveness percent
ORAL CONTRACEPTIVES Breast tenderness, weight gain or loss, bleeding between periods, nausea, decreased sex drive 99.9
INTRAUTERINE DEVICES (IUDs) Spotty bleeding between periods, cramps, infection, increased risk of pelvic inflammatory disease, infertility, uterine puncture #
NORPLANT Irregular bleeding, hair loss, headache, increased appetite, possible scarring after insertion or removal, increased risk of pregnancy outside the womb if conception occurs 99.9
DEPO PROVERA Nausea, breast soreness, irregular bleeding, headache, increased appetite, weight gain, nervousness, hair loss 99.7
FEMALE CONDOMS Irritation to vagina and vulva in some women, and to the penis in some men 95
CONTRACEPTIVE SPONGE Allergic reactions 90
EMERGENCY CONTRACEPTIVES (BIRTH-CONTROL PILLS) Nausea, vomiting, cramps, breast tenderness, irregular bleeding, headaches 75, IF USED WITHIN 72 HOURS
MALE CONDOM Latex allergy (rare) 97
CERVICAL CAP, DIAPHRAGM Irritation or infection from spermicides used with them. Cap: abnormal cervical cell growth, Diaphragm: bladder infection, toxic shock syndrome (rare) 80-90, 94
STERILIZATION (TUBAL LIGATION, VASECTOMY) For women, bleeding, infection, reaction to anesthetic. For men, infection (rare) 99.5, 99.9
CONTRACEPTIVE FOAMS, CREAMS AND GELS (SPERMICIDES) Possible skin irritation, increased risk of bacterial vaginosis or yeast infection 94

 

Methods STD protection Convenience effectiveness percent
ORAL CONTRACEPTIVES No Taken once a day 99.9
INTRAUTERINE DEVICES (IUDs) No Inserted once by a clinician. Offers protection for one to ten years #
NORPLANT No Inserted under the skin of the upper arm. Lasts five years 99.9
DEPO PROVERA No The shot has to be taken every three months 99.7
FEMALE CONDOMS Yes Must be inserted before each act of sexual intercourse. Can be inserted up to eight hours before sex 95
CONTRACEPTIVE SPONGE No One sponge can be used for repeated acts of intercourse, Can be inserted several hours before sex 90
EMERGENCY CONTRACEPTIVES (BIRTH-CONTROL PILLS) No Can take Preven, a prepack-aged emergency contraceptive kit, or use ordinary birth-control pills, following instructions from a clinician 75, IF USED WITHIN 72 HOURS
MALE CONDOM Yes New condom must be placed over the penis before each act of sexual intercourse 97
CERVICAL CAP, DIAPHRAGM No Fitted by a clinician. Must be placed in the vagina and over the cervix before sexual intercourse. Must stay in place 8 hours after sex but no more than 24 hours 80-90, 94
STERILIZATION (TUBAL LIGATION, VASECTOMY) No Surgical procedure done once 99.5, 99.9
CONTRACEPTIVE FOAMS, CREAMS AND GELS (SPERMICIDES) Yes, for certain STD Must be inserted in the vagina before each act of sexual intercourse 94

 

Methods Availability effectiveness percent
ORAL CONTRACEPTIVES By prescription 99.9
INTRAUTERINE DEVICES (IUDs) By prescription #
NORPLANT By prescription 99.9
DEPO PROVERA By prescription and administered by a clinician 99.7
FEMALE CONDOMS No prescription needed 95
CONTRACEPTIVE SPONGE No prescription needed 90
EMERGENCY CONTRACEPTIVES (BIRTH-CONTROL PILLS) By prescription 75, IF USED WITHIN 72 HOURS
MALE CONDOM No prescription needed 97
CERVICAL CAP, DIAPHRAGM By prescription 80-90, 94
STERILIZATION (TUBAL LIGATION,VASECTOMY) By appointment with a doctor 99.5, 99.9
CONTRACEPTIVE FOAMS, CREAMS AND GELS (SPERMICIDES) No prescription needed 94

SOURCE: All About Birth Control: The Compete Guide by Planned Parenthood (Three Rivers Press, $12).

Deborah L. Shelton is a public health and science reporter. She lives in Chicago.3

COPYRIGHT 1999 Essence Communications, Inc.
COPYRIGHT 2000 Gale Group





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